Uncovering the full diversity of B cell repertoires is key to understanding immunological disease and driving efficient antibody discovery campaigns. Parse Evercode™ BCR bolsters such efforts through simultaneous profiling full-length BCR sequences and the whole transcriptome with single cell resolution. Here, we highlight several exciting antibody discovery applications of Evercode BCR including:
- Profiling human BCR clonal diversity in autoimmune disease
- Characterizing of differential B cell V gene usage across common mouse strains
- Mining B cell repertoire in a humanized mouse model under naive and immunized conditions
